EML4-ALK

2-7% of patients with non-small cell lung cancer (NSCLC) have a rearrangement of the EML4 and ALK genes. Both genes are located on the short arm of chromosome 2. To date there are 15 different fusion transcript variants identified. The V1, V2 and V3a/b variants make up 72-80% of all EML4/ALK chimeric transcripts. The ViroGene kit is able to detect these three variants with high sensitivity and specifity.